This advanced diagnostic bundle enhances early detection of ovarian tumours by combining biomarker analysis and imaging. It includes HE4 and CA125 blood tests, integrated into the ROMA algorithm to stratify ovarian cancer risk, alongside a transvaginal ultrasound for structural evaluation of ovaries/pelvis. Designed for accuracy and convenience, the bundle aids in distinguishing benign from malignant pathology, supporting timely intervention and improved outcomes through a proactive, evidence-based approach to ovarian health.