Ground breaking new research from England shows that the HPV vaccine is saving lives – and the results are nothing short of remarkable.
A major study published in June 2026 has found that girls vaccinated against HPV (human papillomavirus) at age 12–13 have experienced a dramatic reduction in cervical cancer deaths, including an estimated 100% reduction in deaths among women aged 20–24 between 2020 and 2024. The findings add real-world weight to the importance of regular sexual health screening alongside vaccination.
What the Study Found
The research, which analysed data from England’s HPV vaccination programme (introduced in 2008), revealed some truly encouraging findings.
Zero Deaths in Vaccinated Cohort
Zero cervical cancer deaths were recorded in women aged 20–24 during 2020–2024 – the first cohort to have been vaccinated as young teenagers.
Reductions Across Age Groups
Overall, high vaccination coverage has been linked to large reductions in cervical cancer deaths across young age groups.
Fewer Precancerous Lesions
The study also showed significant reductions in cervical cancer incidence and the number of precancerous lesions in vaccinated cohorts.
Why This Matters
How HPV Causes Cervical Cancer
HPV (human papillomavirus) is responsible for the vast majority of cervical cancers. Vaccination before exposure to the virus greatly lowers the risk of developing cervical cancer later in life.
Vaccine Uptake in the UK
The HPV vaccine has been available in the UK since 2008, initially offered to girls aged 12–13. Uptake has been high, and these results show that the vaccine is working exactly as intended. The findings support the idea that widespread vaccination can help countries move toward eliminating cervical cancer as a public health problem.
What This Means for You
If You Have a Daughter Aged 12–13
Make sure she receives the HPV vaccine as part of the routine school programme. This study shows that early vaccination offers the best protection.
If You Missed the Vaccine as a Teenager
Many health services offer catch-up programmes for older teenagers and young adults. It’s never too late to benefit.
If You’re an Adult Woman
Continue attending your regular cervical screening (smear tests) when invited. The vaccine does not replace screening, especially for women who were not vaccinated or for older age groups. You should also speak to your gynaecologist about whether you would benefit from adult HPV vaccination.
Continue Regular Cervical Screening
Routine screening remains an essential part of your well woman health check, regardless of your vaccination status.
Why Screening Still Matters After Vaccination
The vaccine protects against the HPV types responsible for most cervical cancers, but it does not cover every type. Screening remains the best way to catch changes early, before they develop into cancer.
Special Considerations for Older or Unvaccinated Women
If you were not vaccinated as a teenager, or if you are outside the standard vaccination age range, screening becomes even more important. Speak to your gynaecologist about your individual risk and whether catch-up vaccination is appropriate for you.
Safety and Common Questions
Is the HPV Vaccine Safe?
Yes. HPV vaccines have been used widely for many years and are considered safe. Side effects are usually mild – soreness at the injection site, or a brief fever.
Does It Protect Against All Cervical Cancers?
The vaccine protects against the HPV types that cause most cervical cancers and some other cancers, including cancers of the vulva, vagina, and throat.
Why Is It Given So Early?
The vaccine works best when given before any exposure to HPV – which is why it’s offered to young teenagers.
How to Protect Yourself and Your Family
- Talk to your GP, school health service, or local sexual health clinic about vaccination
- Check your cervical screening history – if you’re due for a smear test, book it
- Share this information with other women and parents in your life – awareness saves lives
Bottom Line
This study adds strong real-world evidence that high HPV vaccine uptake in early adolescence can prevent cervical cancer deaths.
The HPV vaccine works. If you or your child hasn’t been vaccinated, or if you’re unsure about screening, contact us for a confidential consultation. Vaccination and screening together are your best protection against cervical cancer.
About the Author – Mr Javaid Muglu, Consultant Gynaecologist
eGynaecologist